![\"\"](\"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2021\/07\/800-0-7131fdbd7fad9d28e6a3dcde3db73a4d.jpeg?resize=486%2C287&ssl=1\")
<\/p>\n<\/p>\n
Pse po p\u00ebrhapen m\u00eb leht\u00eb variantet e reja t\u00eb SARS-CoV-2? Ekspert\u00ebt japin ALARMIN<\/p>\n
20 KORRIK 2021<\/p>\n
Si t\u00eb gjitha organizmat e gjalla edhe viruset kan\u00eb ciklet e tyre jet\u00ebsore. Ato jan\u00eb parazitare, duke filluar n\u00eb momentin kur nj\u00eb virus-prind infekton nj\u00eb krijes\u00eb tjet\u00ebr dhe pushton qelizat e tij p\u00ebr t\u00eb b\u00ebr\u00eb kopje t\u00eb vetvetes.<\/p>\n
N\u00eb rastin e SARS-CoV-2, virusi q\u00eb po shkakton pandemin\u00eb aktuale, kjo ndodh kur virusi dep\u00ebrton p\u00ebrmes nj\u00eb enzime t\u00eb quajtur ACE2 n\u00eb membran\u00ebn e disa qelizave njer\u00ebzore, dhe rr\u00ebshqet n\u00eb gjenom\u00ebn e saj. Ky pushtim qelizor ndihmohet nga nj\u00eb protein\u00eb q\u00eb e studion sip\u00ebrfaqen e virusit.<\/p>\n
Ndryshimet n\u00eb k\u00ebt\u00eb protein\u00eb, t\u00eb nxitura nga ndryshimet gjenetike p\u00ebr shkak t\u00eb mutacionit, ndryshojn\u00eb edhe vetit\u00eb e p\u00ebrgjithshme t\u00eb virusit, dhe sidomos aft\u00ebsin\u00eb e tij p\u00ebr t\u2019u p\u00ebrhapur n\u00ebp\u00ebr popullata. Natyra e ndryshueshme e viruseve,e ka burimin tek rast\u00ebsia e natyrshme q\u00eb ndodh brenda procesit t\u00eb prodhimit t\u00eb kopjeve t\u00eb \u00e7do objekti, duke i b\u00ebr\u00eb t\u00eb pashmangshmegabimet, t\u00eb cilat quhen mutacione.<\/p>\n
Shumica d\u00ebrrmuese e viruseve nuk i mbijetojn\u00eb dot gabimeve n\u00eb procesin e shumimit.<\/p>\n
Por disa po, dhe madje mund t\u00eb lul\u00ebzojn\u00eb si rezultat i k\u00ebtyre ndryshimeve, duke e fituar konkurrenc\u00ebn me viruset paraardh\u00ebs, dhe duke u p\u00ebrhapur n\u00eb nj\u00eb m\u00ebnyr\u00eb m\u00eb efikase n\u00ebp\u00ebr popullat\u00ebn e tyre prit\u00ebse.<\/p>\n
Ekzistojn\u00eb disa pjes\u00eb t\u00eb struktur\u00ebs s\u00eb virusit, t\u00eb cilat jan\u00eb m\u00eb t\u00eb afta t\u00eb p\u00ebrballojn\u00eb mutacionet:proteina q\u00eb vesh nga jasht\u00eb virusin \u00ebsht\u00eb m\u00eb tolerante ndaj ndryshimeve. Viruset q\u00eb p\u00ebsojn\u00eb mutacione dhe mbijetojn\u00eb quhen variante. Ato nis\u00ebn t\u00eb shfaqeshin n\u00eb n\u00ebntorin e vitit t\u00eb kaluar, me variantin Alfa q\u00eb u zbulua fillimisht n\u00eb Kent, n\u00eb juglindje t\u00eb Anglis\u00eb.<\/p>\n
Variantet e reja, duhet se kan\u00eb prioritet n\u00eb krahasim me ato t\u00eb vjetrat, n\u00ebse shnd\u00ebrrohen n\u00eb form\u00ebn dominuese t\u00eb virusit.<\/p>\n
Nj\u00eb nga mutacionet e para q\u00eb rrit transmetueshm\u00ebrin\u00eb u njoh si N501Y ose\u201cNelly\u201d, nj\u00eb nga tet\u00eb mutacionet q\u00eb karakterizuan protein\u00ebn virale t\u00eb variantit Alfa. Emri teknik i mutacionit i referohet ndryshimeve n\u00eb gjenomin e virusit. \u201c501\u201d do t\u00eb thot\u00eb q\u00eb ndryshimi po ndodh n\u00eb aminoacidin 501 n\u00eb nj\u00eb zinxhir prej 1.273 t\u00eb tilla q\u00eb p\u00ebrb\u00ebjn\u00eb protein\u00ebn virale.<\/p>\n
Meqen\u00ebse aminoacidet e ndryshme kan\u00eb veti kimike paksa t\u00eb ndryshme, ky ndryshim ka nj\u00eb ndikim n\u00eb struktur\u00ebn e protein\u00ebs mb\u00ebshtjell\u00ebse.<\/p>\n
P\u00ebr pasoj\u00eb ndryshon edhe m\u00ebnyra e shp\u00ebrndarjes s\u00eb ngarkes\u00ebs elektrike. Kjo nga ana e saj ndryshon paksa form\u00ebn e protein\u00ebs, pasi zonat me ngarkes\u00eb elektrike pozitive t\u00ebrheqin zona me ngarkes\u00eb negative. Fal\u00eb k\u00ebsaj dinamike, N501Y lejon q\u00eb nj\u00eb pjes\u00eb thelb\u00ebsore e kulmit t\u00eb rrotullohet rreth 20 grad\u00eb, duke b\u00ebr\u00eb q\u00eb t\u00eb p\u00ebrshtatet m\u00eb mir\u00eb me receptorin ACE2.<\/p>\n
Kjo gj\u00eb e rrit transmetueshm\u00ebrin\u00eb. Mutacione t\u00eb tjera kryejn\u00eb nj\u00eb truk t\u00eb ngjash\u00ebm Delta, varianti q\u00eb u zbulua p\u00ebr her\u00eb t\u00eb par\u00eb n\u00eb Indi dhe q\u00eb aktualisht po p\u00ebrhapet n\u00eb t\u00eb gjith\u00eb bot\u00ebn, duket t\u00eb jet\u00eb edhe m\u00eb i transmetuesh\u00ebm se Alfa dhe variantet e tjera. Edhe pse nuk \u00ebsht\u00eb e qart\u00eb, pasi studimet e holl\u00ebsishme strukturore mbi protein\u00ebn e k\u00ebtij varianti nuk kan\u00eb p\u00ebrfunduar ende.<\/p>\n
Por Ravindra Gupta, virolog molekular n\u00eb Universitetin e Kembrixhit dhe koleg\u00ebt e tij argumentojn\u00eb se transmetueshm\u00ebria e shtuar e Delta ka t\u00eb b\u00ebj\u00eb pjes\u00ebrisht me nj\u00eb mutacion n\u00eb vendin aminoacidin nr.681. Kjo \u00ebsht\u00eb pika n\u00eb maj\u00eb ku lidhet me ACE2, dhe proteina virale \u00e7ahet m\u00eb dysh.<\/p>\n
Nd\u00ebrkoh\u00eb ekzistojn\u00eb edhe mutacione t\u00eb tjera teorike q\u00eb e b\u00ebjn\u00eb virusin m\u00eb t\u00eb transmetuesh\u00ebm dhe t\u00eb cilat ai nuk i ka arritur akoma. Por edhe t\u00eb tjer\u00eb q\u00eb e ndihmojn\u00eb at\u00eb t\u00eb shmang\u00eb antitrupat q\u00eb l\u00ebshon sistemi imunitar n\u00eb m\u00ebnyr\u00eb q\u00eb t\u00eb mbroj\u00eb trupin nga infeksioni. Bota.al<\/p>\n
Nga Gazeta Sot<\/p>\n","protected":false},"excerpt":{"rendered":"
Pse po p\u00ebrhapen m\u00eb leht\u00eb variantet e reja t\u00eb SARS-CoV-2? Ekspert\u00ebt japin ALARMIN 20 KORRIK 2021 Si t\u00eb gjitha organizmat e gjalla edhe viruset kan\u00eb ciklet e tyre jet\u00ebsore. Ato jan\u00eb parazitare, duke filluar n\u00eb momentin kur nj\u00eb virus-prind infekton nj\u00eb krijes\u00eb tjet\u00ebr dhe pushton qelizat e tij p\u00ebr t\u00eb b\u00ebr\u00eb kopje t\u00eb vetvetes. N\u00eb […]<\/p>\n","protected":false},"author":9,"featured_media":48679,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[27,35],"tags":[],"class_list":["post-48677","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogu-i-udhetarit","category-shoqerore"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2021\/07\/800-0-7131fdbd7fad9d28e6a3dcde3db73a4d.jpeg?fit=800%2C471&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5Z6wp-cF7","jetpack-related-posts":[{"id":104821,"url":"https:\/\/www.shqiperia.com\/blog\/studimi-tregon-se-thatesirat-ndryshojne-perhapjen-e-semundjeve-infektive\/","url_meta":{"origin":48677,"position":0},"title":"Studimi tregon se that\u00ebsirat ndryshojn\u00eb p\u00ebrhapjen e s\u00ebmundjeve infektive","author":"Kurt Farka","date":"August 20, 2026","format":false,"excerpt":"20 Gusht 2026 Nga Per\u00ebndimi amerikan deri n\u00eb Europ\u00eb, that\u00ebsirat po thajn\u00eb lumenjt\u00eb, po nxisin zjarre shkat\u00ebrruese dhe po ndryshojn\u00eb ekosistemet. Por ato po ndikojn\u00eb edhe n\u00eb m\u00ebnyr\u00ebn se si p\u00ebrhapen s\u00ebmundjet infektive, duke shkaktuar rritje t\u00eb rasteve t\u00eb s\u00ebmundjeve si kolera dhe virusi i Nilit Per\u00ebndimor. Nj\u00eb studim i\u2026","rel":"","context":"In "Blogu i Udh\u00ebtarit"","block_context":{"text":"Blogu i Udh\u00ebtarit","link":"https:\/\/www.shqiperia.com\/blog\/category\/blogu-i-udhetarit\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/auto_drought-is-reshaping-t1787216309.jpg?fit=900%2C596&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/auto_drought-is-reshaping-t1787216309.jpg?fit=900%2C596&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/auto_drought-is-reshaping-t1787216309.jpg?fit=900%2C596&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/auto_drought-is-reshaping-t1787216309.jpg?fit=900%2C596&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":103805,"url":"https:\/\/www.shqiperia.com\/blog\/toka-po-behet-me-e-erret-shkencetaret-japin-alarmin-ngrohja-globale-po-pershpejton-ndryshimin-e-planetit\/","url_meta":{"origin":48677,"position":1},"title":"Toka po b\u00ebhet m\u00eb e err\u00ebt, shkenc\u00ebtar\u00ebt japin alarmin: – Ngrohja globale po p\u00ebrshpejton ndryshimin e planetit","author":"Kurt Farka","date":"August 4, 2026","format":false,"excerpt":"4 Gusht 2026 Ndryshimi i klim\u00ebs nuk po matet vet\u00ebm p\u00ebrmes rritjes s\u00eb temperaturave. Nj\u00eb tjet\u00ebr tregues shqet\u00ebsues q\u00eb po v\u00ebzhgojn\u00eb shkenc\u00ebtar\u00ebt \u00ebsht\u00eb edhe ndryshimi i shk\u00eblqimit t\u00eb Tok\u00ebs: planeti po humbet gradualisht aft\u00ebsin\u00eb e tij natyrore p\u00ebr t\u00eb reflektuar rrezet e Diellit drejt hap\u00ebsir\u00ebs. Ky fenomen njihet si ulja\u2026","rel":"","context":"In "Blogu i Udh\u00ebtarit"","block_context":{"text":"Blogu i Udh\u00ebtarit","link":"https:\/\/www.shqiperia.com\/blog\/category\/blogu-i-udhetarit\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/b78dde7c-ap19227568082481.jpg?fit=1200%2C720&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/b78dde7c-ap19227568082481.jpg?fit=1200%2C720&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/b78dde7c-ap19227568082481.jpg?fit=1200%2C720&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/b78dde7c-ap19227568082481.jpg?fit=1200%2C720&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/08\/b78dde7c-ap19227568082481.jpg?fit=1200%2C720&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":102624,"url":"https:\/\/www.shqiperia.com\/blog\/anticikloni-afrikan-sjell-vale-te-forta-te-nxehti-ne-europe-italia-ngre-alarmin-edhe-shqiperia-perfshihet-nga-temperaturat-e-larta\/","url_meta":{"origin":48677,"position":2},"title":"Anticikloni afrikan sjell val\u00eb t\u00eb forta t\u00eb nxehti n\u00eb Europ\u00eb\/ Italia ngre alarmin, edhe Shqip\u00ebria p\u00ebrfshihet nga temperaturat e larta","author":"Kurt Farka","date":"July 13, 2026","format":false,"excerpt":"13 Korrik 2926 Nj\u00eb val\u00eb e fort\u00eb nxeht\u00ebsie po prek pjes\u00eb t\u00eb m\u00ebdha t\u00eb Evrop\u00ebs, nd\u00ebrsa meteorolog\u00ebt shpjegojn\u00eb se shkak kryesor \u00ebsht\u00eb rikthimi i anticiklonit afrikan, nj\u00eb mas\u00eb ajrore e nxeht\u00eb q\u00eb vjen nga Afrika e Veriut dhe sjell temperatura ekstreme. 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Alarm global p\u00ebr virusin e Ebolas n\u00eb Afrik\u00eb, OBSH shpall emergjenc\u00eb nd\u00ebrkomb\u00ebtare","author":"Kurt Farka","date":"May 18, 2026","format":false,"excerpt":"18 Maji 2026 Dit\u00ebt e fundit, bota \u00ebsht\u00eb panikosur nga\u00a0 p\u00ebrhapja e pakontrolluar e virusit Ebola n\u00eb Republik\u00ebn Demokratike t\u00eb Kongos. Autoritetet sh\u00ebndet\u00ebsore paralajm\u00ebrojn\u00eb se p\u00ebrballimi i virusit \u00ebsht\u00eb b\u00ebr\u00eb tep\u00ebr i komplikuar, nd\u00ebrsa varianti aktual i Ebol\u00ebs konsiderohet i rrall\u00eb dhe me pak mund\u00ebsi trajtimi. 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