![\"\"](\"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2021\/07\/800-0-7131fdbd7fad9d28e6a3dcde3db73a4d.jpeg?resize=486%2C287&ssl=1\")
<\/p>\n<\/p>\n
Pse po p\u00ebrhapen m\u00eb leht\u00eb variantet e reja t\u00eb SARS-CoV-2? Ekspert\u00ebt japin ALARMIN<\/p>\n
20 KORRIK 2021<\/p>\n
Si t\u00eb gjitha organizmat e gjalla edhe viruset kan\u00eb ciklet e tyre jet\u00ebsore. Ato jan\u00eb parazitare, duke filluar n\u00eb momentin kur nj\u00eb virus-prind infekton nj\u00eb krijes\u00eb tjet\u00ebr dhe pushton qelizat e tij p\u00ebr t\u00eb b\u00ebr\u00eb kopje t\u00eb vetvetes.<\/p>\n
N\u00eb rastin e SARS-CoV-2, virusi q\u00eb po shkakton pandemin\u00eb aktuale, kjo ndodh kur virusi dep\u00ebrton p\u00ebrmes nj\u00eb enzime t\u00eb quajtur ACE2 n\u00eb membran\u00ebn e disa qelizave njer\u00ebzore, dhe rr\u00ebshqet n\u00eb gjenom\u00ebn e saj. Ky pushtim qelizor ndihmohet nga nj\u00eb protein\u00eb q\u00eb e studion sip\u00ebrfaqen e virusit.<\/p>\n
Ndryshimet n\u00eb k\u00ebt\u00eb protein\u00eb, t\u00eb nxitura nga ndryshimet gjenetike p\u00ebr shkak t\u00eb mutacionit, ndryshojn\u00eb edhe vetit\u00eb e p\u00ebrgjithshme t\u00eb virusit, dhe sidomos aft\u00ebsin\u00eb e tij p\u00ebr t\u2019u p\u00ebrhapur n\u00ebp\u00ebr popullata. Natyra e ndryshueshme e viruseve,e ka burimin tek rast\u00ebsia e natyrshme q\u00eb ndodh brenda procesit t\u00eb prodhimit t\u00eb kopjeve t\u00eb \u00e7do objekti, duke i b\u00ebr\u00eb t\u00eb pashmangshmegabimet, t\u00eb cilat quhen mutacione.<\/p>\n
Shumica d\u00ebrrmuese e viruseve nuk i mbijetojn\u00eb dot gabimeve n\u00eb procesin e shumimit.<\/p>\n
Por disa po, dhe madje mund t\u00eb lul\u00ebzojn\u00eb si rezultat i k\u00ebtyre ndryshimeve, duke e fituar konkurrenc\u00ebn me viruset paraardh\u00ebs, dhe duke u p\u00ebrhapur n\u00eb nj\u00eb m\u00ebnyr\u00eb m\u00eb efikase n\u00ebp\u00ebr popullat\u00ebn e tyre prit\u00ebse.<\/p>\n
Ekzistojn\u00eb disa pjes\u00eb t\u00eb struktur\u00ebs s\u00eb virusit, t\u00eb cilat jan\u00eb m\u00eb t\u00eb afta t\u00eb p\u00ebrballojn\u00eb mutacionet:proteina q\u00eb vesh nga jasht\u00eb virusin \u00ebsht\u00eb m\u00eb tolerante ndaj ndryshimeve. Viruset q\u00eb p\u00ebsojn\u00eb mutacione dhe mbijetojn\u00eb quhen variante. Ato nis\u00ebn t\u00eb shfaqeshin n\u00eb n\u00ebntorin e vitit t\u00eb kaluar, me variantin Alfa q\u00eb u zbulua fillimisht n\u00eb Kent, n\u00eb juglindje t\u00eb Anglis\u00eb.<\/p>\n
Variantet e reja, duhet se kan\u00eb prioritet n\u00eb krahasim me ato t\u00eb vjetrat, n\u00ebse shnd\u00ebrrohen n\u00eb form\u00ebn dominuese t\u00eb virusit.<\/p>\n
Nj\u00eb nga mutacionet e para q\u00eb rrit transmetueshm\u00ebrin\u00eb u njoh si N501Y ose\u201cNelly\u201d, nj\u00eb nga tet\u00eb mutacionet q\u00eb karakterizuan protein\u00ebn virale t\u00eb variantit Alfa. Emri teknik i mutacionit i referohet ndryshimeve n\u00eb gjenomin e virusit. \u201c501\u201d do t\u00eb thot\u00eb q\u00eb ndryshimi po ndodh n\u00eb aminoacidin 501 n\u00eb nj\u00eb zinxhir prej 1.273 t\u00eb tilla q\u00eb p\u00ebrb\u00ebjn\u00eb protein\u00ebn virale.<\/p>\n
Meqen\u00ebse aminoacidet e ndryshme kan\u00eb veti kimike paksa t\u00eb ndryshme, ky ndryshim ka nj\u00eb ndikim n\u00eb struktur\u00ebn e protein\u00ebs mb\u00ebshtjell\u00ebse.<\/p>\n
P\u00ebr pasoj\u00eb ndryshon edhe m\u00ebnyra e shp\u00ebrndarjes s\u00eb ngarkes\u00ebs elektrike. Kjo nga ana e saj ndryshon paksa form\u00ebn e protein\u00ebs, pasi zonat me ngarkes\u00eb elektrike pozitive t\u00ebrheqin zona me ngarkes\u00eb negative. Fal\u00eb k\u00ebsaj dinamike, N501Y lejon q\u00eb nj\u00eb pjes\u00eb thelb\u00ebsore e kulmit t\u00eb rrotullohet rreth 20 grad\u00eb, duke b\u00ebr\u00eb q\u00eb t\u00eb p\u00ebrshtatet m\u00eb mir\u00eb me receptorin ACE2.<\/p>\n
Kjo gj\u00eb e rrit transmetueshm\u00ebrin\u00eb. Mutacione t\u00eb tjera kryejn\u00eb nj\u00eb truk t\u00eb ngjash\u00ebm Delta, varianti q\u00eb u zbulua p\u00ebr her\u00eb t\u00eb par\u00eb n\u00eb Indi dhe q\u00eb aktualisht po p\u00ebrhapet n\u00eb t\u00eb gjith\u00eb bot\u00ebn, duket t\u00eb jet\u00eb edhe m\u00eb i transmetuesh\u00ebm se Alfa dhe variantet e tjera. Edhe pse nuk \u00ebsht\u00eb e qart\u00eb, pasi studimet e holl\u00ebsishme strukturore mbi protein\u00ebn e k\u00ebtij varianti nuk kan\u00eb p\u00ebrfunduar ende.<\/p>\n
Por Ravindra Gupta, virolog molekular n\u00eb Universitetin e Kembrixhit dhe koleg\u00ebt e tij argumentojn\u00eb se transmetueshm\u00ebria e shtuar e Delta ka t\u00eb b\u00ebj\u00eb pjes\u00ebrisht me nj\u00eb mutacion n\u00eb vendin aminoacidin nr.681. Kjo \u00ebsht\u00eb pika n\u00eb maj\u00eb ku lidhet me ACE2, dhe proteina virale \u00e7ahet m\u00eb dysh.<\/p>\n
Nd\u00ebrkoh\u00eb ekzistojn\u00eb edhe mutacione t\u00eb tjera teorike q\u00eb e b\u00ebjn\u00eb virusin m\u00eb t\u00eb transmetuesh\u00ebm dhe t\u00eb cilat ai nuk i ka arritur akoma. Por edhe t\u00eb tjer\u00eb q\u00eb e ndihmojn\u00eb at\u00eb t\u00eb shmang\u00eb antitrupat q\u00eb l\u00ebshon sistemi imunitar n\u00eb m\u00ebnyr\u00eb q\u00eb t\u00eb mbroj\u00eb trupin nga infeksioni. Bota.al<\/p>\n
Nga Gazeta Sot<\/p>\n","protected":false},"excerpt":{"rendered":"
Pse po p\u00ebrhapen m\u00eb leht\u00eb variantet e reja t\u00eb SARS-CoV-2? Ekspert\u00ebt japin ALARMIN 20 KORRIK 2021 Si t\u00eb gjitha organizmat e gjalla edhe viruset kan\u00eb ciklet e tyre jet\u00ebsore. Ato jan\u00eb parazitare, duke filluar n\u00eb momentin kur nj\u00eb virus-prind infekton nj\u00eb krijes\u00eb tjet\u00ebr dhe pushton qelizat e tij p\u00ebr t\u00eb b\u00ebr\u00eb kopje t\u00eb vetvetes. N\u00eb […]<\/p>\n","protected":false},"author":9,"featured_media":48679,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[27,35],"tags":[],"class_list":["post-48677","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogu-i-udhetarit","category-shoqerore"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2021\/07\/800-0-7131fdbd7fad9d28e6a3dcde3db73a4d.jpeg?fit=800%2C471&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5Z6wp-cF7","jetpack-related-posts":[{"id":100659,"url":"https:\/\/www.shqiperia.com\/blog\/ekspertet-ngrene-alarmin-popullsia-e-tokes-mund-te-pergjysmohet-deri-ne-vitin-2064-shkak-pandemite-ndryshimet-klimatike-dhe\/","url_meta":{"origin":48677,"position":0},"title":"Ekspert\u00ebt ngren\u00eb alarmin\/ Popullsia e Tok\u00ebs mund t\u00eb p\u00ebrgjysmohet deri n\u00eb vitin 2064, shkak pandemit\u00eb, ndryshimet klimatike dhe\u2026","author":"Kurt Farka","date":"May 26, 2026","format":false,"excerpt":"26 Maji 2026 Ekspert\u00ebt paralajm\u00ebrojn\u00eb se popullsia e Tok\u00ebs mund t\u00eb p\u00ebrgjysmohet deri n\u00eb vitin 2064, si pasoj\u00eb e krizave globale si ndryshimet klimatike, pandemit\u00eb, konfliktet apo mungesa e burimeve. Sipas nj\u00eb studimi t\u00eb publikuar n\u00eb revist\u00ebn shkencore Chaos, Solitons & Fractals, studiuesit nga Universiteti i Milanit analizuan rritjen e\u2026","rel":"","context":"In "Blogu i Udh\u00ebtarit"","block_context":{"text":"Blogu i Udh\u00ebtarit","link":"https:\/\/www.shqiperia.com\/blog\/category\/blogu-i-udhetarit\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/toka_sd-1.webp?fit=1200%2C675&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/toka_sd-1.webp?fit=1200%2C675&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/toka_sd-1.webp?fit=1200%2C675&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/toka_sd-1.webp?fit=1200%2C675&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/toka_sd-1.webp?fit=1200%2C675&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":100377,"url":"https:\/\/www.shqiperia.com\/blog\/situata-del-jashte-kontrollit-alarm-global-per-virusin-e-ebolas-ne-afrike-obsh-shpall-emergjence-nderkombetare\/","url_meta":{"origin":48677,"position":1},"title":"Situata del jasht\u00eb kontrollit! Alarm global p\u00ebr virusin e Ebolas n\u00eb Afrik\u00eb, OBSH shpall emergjenc\u00eb nd\u00ebrkomb\u00ebtare","author":"Kurt Farka","date":"May 18, 2026","format":false,"excerpt":"18 Maji 2026 Dit\u00ebt e fundit, bota \u00ebsht\u00eb panikosur nga\u00a0 p\u00ebrhapja e pakontrolluar e virusit Ebola n\u00eb Republik\u00ebn Demokratike t\u00eb Kongos. Autoritetet sh\u00ebndet\u00ebsore paralajm\u00ebrojn\u00eb se p\u00ebrballimi i virusit \u00ebsht\u00eb b\u00ebr\u00eb tep\u00ebr i komplikuar, nd\u00ebrsa varianti aktual i Ebol\u00ebs konsiderohet i rrall\u00eb dhe me pak mund\u00ebsi trajtimi. 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Disa analist\u00eb presin q\u00eb \u00e7mimet t\u00eb vazhdojn\u00eb t\u00eb rriten mes nj\u00eb mjedisi\u2026","rel":"","context":"In "Njoftime Shtypi"","block_context":{"text":"Njoftime Shtypi","link":"https:\/\/www.shqiperia.com\/blog\/category\/njoftime-shtypi\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/900-0-1757092900xshutterstock-2480509399-2024-08-368b960cfc07a7fc6986b47f60f0159d-scaled-298.webp?fit=900%2C506&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/900-0-1757092900xshutterstock-2480509399-2024-08-368b960cfc07a7fc6986b47f60f0159d-scaled-298.webp?fit=900%2C506&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/900-0-1757092900xshutterstock-2480509399-2024-08-368b960cfc07a7fc6986b47f60f0159d-scaled-298.webp?fit=900%2C506&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.shqiperia.com\/blog\/wp-content\/uploads\/2026\/05\/900-0-1757092900xshutterstock-2480509399-2024-08-368b960cfc07a7fc6986b47f60f0159d-scaled-298.webp?fit=900%2C506&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":100205,"url":"https:\/\/www.shqiperia.com\/blog\/media-amerikane-ngre-alarmin-shqiperia-eshte-kercenimi-me-i-ri-i-botes-si-narkoshtet\/","url_meta":{"origin":48677,"position":4},"title":"Media amerikane ngre alarmin: – Shqip\u00ebria \u00ebsht\u00eb k\u00ebrc\u00ebnimi m\u00eb i ri i bot\u00ebs si narkoshtet","author":"Kurt Farka","date":"May 13, 2026","format":false,"excerpt":"13 Maji 2026 Nga Michael Rubin \u2013\u00a0Washington Examiner\/ Me mij\u00ebra t\u00eb vdekur n\u00eb p\u00ebrshkall\u00ebzimin e fundit t\u00eb luftimeve mes Hezbollahut dhe Izraelit n\u00eb Liban, \u00ebsht\u00eb e v\u00ebshtir\u00eb t\u00eb imagjinosh se Libani dikur ishte nj\u00eb oaz\u00eb paqeje dhe tolerance. 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